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bovine spongiform encephalopathy -definition of bovine spongiform encephalopathy by MedicineWord.com,a Medicine Dictionary

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bovine spongiform encephalopathy A new disease of cattle, first reported in 1986 in Great Britain, characterised clinically by apprehensive behaviour, hyperesthesia, and ataxia and histopathologically by spongiform changes in the gray-matter neuropil of the brain stem; it is thought to be caused by an agent, possibly a prion, similar to that observed as the cause of scrapie. Synonym: mad cow disease.

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