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receptors, tachykinin -definition of receptors, tachykinin by MedicineWord.com,a Medicine Dictionary
©http://medicineword.com From:http://www.medicineword.com/receptors%2C+tachykinin.shtmlThe tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered. The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered. receptors, tachykinin
Cell surface proteins that bind tachykinins with high affinity and trigger intracellular changes influencing the behaviour of cells. Three classes of tachykinin receptors have been characterised, the nk-1, nk-2, and nk-3, which prefer, respectively, substance p, neurokinin a (substance k, neurokinin alpha, neuromedin l), and neurokinin b (neurokinin beta, neuromedin k).
[Brand:Humana Press][Price:$165.00]
Offers a state-of-the-art review by international experts on all aspects of tachykinin receptors, including neuropeptide/peptide and G-protein-linked receptors in general. It covers the physiology, pharmacology, biochemistry, and molecular biology of these receptors from both clinical and basic research points of view. Topics treated by the distinguished contributors include the characterization of tachykinin receptors, the mechanisms of tachykinin receptor action, a reflection on future prospects, and a historical consideration of tachykinin research.
[Brand:Thomson Gale][Price:$9.95]
This digital document is an article from American Journal of Biochemistry and Biotechnology, published by Thomson Gale on September 22, 2007. The length of the article is 4030 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.
Citation Details
Title: Pharmacophore pattern identification of tachykinin receptor selective peptide agonists: implications in receptor selectivity.(Report)
Author: Anjali Dike
Publication: American Journal of Biochemistry and Biotechnology (Magazine/Journal)
Date: September 22, 2007
Publisher: Thomson Gale
Volume: 3 Issue: 4 Page: 180(7)
Article Type: Report
Distributed by Thomson Gale
[Brand:Springer][Price:$539.00]
[Brand:Hephaestus Books][Price:$15.75]
Hephaestus Books represents a new publishing paradigm, allowing disparate content sources to be curated into cohesive, relevant, and informative books. To date, this content has been curated from Wikipedia articles and images under Creative Commons licensing, although as Hephaestus Books continues to increase in scope and dimension, more licensed and public domain content is being added. We believe books such as this represent a new and exciting lexicon in the sharing of human knowledge. This particular book contains chapters focused on Tachykinin receptor antagonists, NK1 receptor antagonists, NK2 receptor antagonists, and NK3 receptor antagonists.
[Brand:Springer][Price:$539.00]
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